Introduction
Founded in 2013 and based in South SanFrancisco, the company has developed a proprietary silicon-based DNA manufacturing platform that “writes” DNA with high precision, throughput, and cost efficiency—transforming how DNA is produced for research and industry.
Twist’s products and tools empower scientists, biotech innovators, and pharmaceutical developers across applications such as genomics, drug discovery, diagnostics, industrial biotechnology, agriculture, and emerging fields like digital DNA data storage.

Next-Generation Sequencing (NGS) Tools and Panels
Twist provides products and NGS target enrichment solutions, including customizable panels for DNA, RNA, and methylation workflows, helping researchers enrich and sequence specific regions of interest efficiently.
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Twist Precision Dx Products
Twist’s Whole Exome Library Preparation Solution intended for use with high-quality genomic DNA derived from human cells such as whole blood, ultimately producing exome-enriched libraries compatible with Next-Generation Sequencing (NGS) applications. The Twist Precision Dx Product offers an EU IVDR-compliant solution with proven performance.

Synthetic Genes & Gene Fragments
Twist offers a broad range of gene synthesis solutions that accelerate research and development. These include clonal (sequence-verified) genes, gene fragments, and rapid turnaround services designed to meet custom research and production needs.

Variant & Combinatorial Libraries
Twist delivers variant libraries—including combinatorial and site-saturation libraries—that support protein engineering, antibody discovery, and deep functional analysis. These custom libraries enable broad exploration of sequence space and targeted mutation












