About Horizon Discovery
Founded in 2005 and headquartered in Cambridge, United Kingdom, Horizon’s solutions help academic researchers, pharmaceutical and biotechnology companies, and clinical laboratories understand gene function, model disease pathways, identify drug targets, and accelerate therapeutic and diagnostic development.
Now part of Revvity, Inc., following acquisition and corporate integration, Horizon’s broad portfolio combines robust research reagents, engineered cell models, reference materials, and custom services to support discovery through to application.
Horizon Discovery offers a wide range of life-science products and solutions across several key categories:
🔬 Gene Editing Tools & Reagents
- Dharmacon™ Edit-R™ CRISPR guide RNA — pre-designed and customizable guide RNAs for targeted gene editing.
- Cas9 Nucleases — protein and mRNA formats for CRISPR-Cas9 editing workflows.
- CRISPR Controls & Knock-in Templates — validation and HDR donor templates for precision editing.
- All-in-one CRISPR vectors and design tools for custom guide RNA development.
🧬 Cell Models & Engineered Cell Lines
- Knockout and Knock-in Cell Lines — a large library of genetically defined models for standard and disease-relevant research.
- Cas9 Stable and CRISPRmod Cell Lines — engineered cells expressing CRISPR components for streamlined workflows.
📊 Screening Libraries
- Cherry Pick Libraries — customizable arrays of siRNA, microRNA, CRISPR crRNA/sgRNA for functional genomic screens.
- Genome-wide screens and pooled libraries to support high-throughput discovery.
📐 Reference Standards & Controls
- Mimix™ Reference Standards — DNA/RNA and genomic controls for assay validation and quality monitoring (e.g., Onco Mix, OncoSpan, Quantitative FFPE standards).
- gDNA and variant reference materials (e.g., KRAS mutation standards) for diagnostic and research assay benchmarking.
🛠️ Gene Modulation & Functional Tools
- CRISPRmod reagents for interference (CRISPRi) and activation (CRISPRa) studies to modulate gene expression.
